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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Bavituximab (Code C49088)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bavituximab

Definition: A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.

Display Name: Bavituximab

Label: Bavituximab

NCI Thesaurus Code: C49088 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1707382  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Bavituximab
BAVITUXIMAB
Chimeric Anti-Phosphotidylserine Monoclonal Antibody
Tarvacin

External Source Codes: 
CAS Registry Number 648904-28-3 (see NLM ChemIDplus info)
FDA UNII Code Q16CT95N25
PDQ Closed Trial Search ID 450954
PDQ Open Trial Search ID 450954 (check for NCI PDQ open clinical trial info)
UMLS CUI C1707382

Other Properties:
     Name Value (qualifiers indented underneath)
code C49088
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Chimeric_Anti-Phosphotidylserine_Monoclonal_Antibody
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49088

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