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Version: 17.06d (Release date: 2017-06-26)
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gp100:280-288(288V) Peptide Vaccine (Code C49042)

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Terms & Properties

Preferred Name: gp100:280-288(288V) Peptide Vaccine

Definition: A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. gp100:280-288(288V) peptide has a valine substitution at amino acid position 288 to improve immunogenicity. Vaccination with gp100:280-288(288V) peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.

Display Name: gp100:280-288(288V) Peptide Vaccine

Label: gp100:280-288(288V) Peptide Vaccine

NCI Thesaurus Code: C49042 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831910  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
gp100:280-288(288V) Peptide Vaccine

External Source Codes: 
NSC Code 683473 (see NCI DTP info)
PDQ Closed Trial Search ID 492712
PDQ Open Trial Search ID 492712 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831910

Other Properties:
     Name Value (qualifiers indented underneath)
code C49042
Contributing_Source CTRP
Legacy_Concept_Name gp100_280-288_288V_Peptide
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49042

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