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Version: 17.06d (Release date: 2017-06-26)
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Ethacrynic Acid (Code C485)

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Terms & Properties

Preferred Name: Ethacrynic Acid

Definition: An unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.

Label: Ethacrynic Acid

NCI Thesaurus Code: C485 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0014963  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
[2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic Acid
EA
Edecrin
ETHACRYNIC ACID
Ethacrynic Acid
Ethacrynic acid

External Source Codes: 
CAS Registry Number 58-54-8 (see NLM ChemIDplus info)
FDA UNII Code M5DP350VZV
ChEBI ID CHEBI:4876 (see ChEBI info)
NSC Code 85791 (see NCI DTP info)
PDQ Closed Trial Search ID 41163
PDQ Open Trial Search ID 41163 (check for NCI PDQ open clinical trial info)
UMLS CUI C0014963

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C13H12Cl2O4
code C485
Contributing_Source FDA
Legacy_Concept_Name Ethacrynic_Acid
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C485

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