|Zibotentan (Code C48430)|
|Terms & Properties|
Preferred Name: Zibotentan
Definition: An orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation.
NCI-GLOSS Definition: A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called endothelin-receptor antagonists.
Display Name: Zibotentan
NCI Metathesaurus Link: C1328193 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||186497-07-4 (see NLM ChemIDplus info)|
|FDA UNII Code||8054MM4902|
|PDQ Closed Trial Search ID||355727|
|PDQ Open Trial Search ID||355727 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|