|Paclitaxel-Loaded Polymeric Micelle (Code C48415)|
|Terms & Properties|
Preferred Name: Paclitaxel-Loaded Polymeric Micelle
Definition: A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer micelle nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.
NCI-GLOSS Definition: A form of the anticancer drug paclitaxel used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used with another drug to treat non-small cell lung cancer. Paclitaxel is mixed with very tiny particles of a substance that makes it easier to dissolve in water. This allows higher doses of paclitaxel to be given. It is a type of antimitotic agent.
Label: Paclitaxel-Loaded Polymeric Micelle
NCI Metathesaurus Link: C1709446 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
|Paclitaxel-Loaded Polymeric Micelle|
|paclitaxel-loaded polymeric micelle|
External Source Codes:
|PDQ Closed Trial Search ID||434427|
|PDQ Open Trial Search ID||434427 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|