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Version: 16.11d (Release date: 2016-11-28)
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Bowman-Birk Inhibitor Concentrate (Code C48381)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bowman-Birk Inhibitor Concentrate

Definition: An extract of soybeans enriched in Bowman-Birk inhibitor (BBI), a soybean-derived, 71-amino acid, polypeptide and serine protease inhibitor with potential chemopreventive activity. Bowman-Birk inhibitor contains distinct inhibitory sites for trypsin and chymotrypsin. Although the exact mechanism by which BBI suppresses carcinogenesis is unknown, its antiproliferative activity appears to be linked to the chymotrypsin inhibitory region.

NCI-GLOSS Definition: A substance being studied in the prevention of cancer. BBIC is made from soybeans, and is a type of serine proteinase inhibitor.

Display Name: Bowman-Birk Inhibitor Concentrate

Label: Bowman-Birk Inhibitor Concentrate

NCI Thesaurus Code: C48381 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1706991  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BBIC
Bowman-Birk Inhibitor Concentrate
Bowman-Birk inhibitor concentrate
Proteinase Inhibitor, Bowman-Birk Soybean

External Source Codes: 
CAS Registry Number 37330-34-0 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 433272
PDQ Open Trial Search ID 433272 (check for NCI PDQ open clinical trial info)
UMLS CUI C1706991

Other Properties:
Name Value (qualifiers indented underneath)
code C48381
Contributing_Source CTRP
Legacy_Concept_Name Bowman-Birk_Inhibitor_Concentrate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48381

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