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Version: 17.06d (Release date: 2017-06-26)
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Triamcinolone Acetonide (Code C48027)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Triamcinolone Acetonide

Definition: The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.

Label: Triamcinolone Acetonide

NCI Thesaurus Code: C48027 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0040866  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
AllerNaze
Aristocort A
Kenalog
Nasacort
TRIAMCINOLONE ACETONIDE
Triamcinolone Acetonide

External Source Codes: 
CAS Registry Number 76-25-5 (see NLM ChemIDplus info)
FDA UNII Code F446C597KA
NSC Code 21916 (see NCI DTP info)
PDQ Closed Trial Search ID 649799
PDQ Open Trial Search ID 649799 (check for NCI PDQ open clinical trial info)
UMLS CUI C0040866

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Allergic Rhinitis
Chemical_Formula C24H31FO6
code C48027
Contributing_Source FDA
Legacy_Concept_Name Triamcinolone_Acetonide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48027

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