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Version: 16.11d (Release date: 2016-11-28)
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Oxycodone Hydrochloride (Code C48010)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Oxycodone Hydrochloride

Definition: The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism.

NCI-GLOSS Definition: A drug used to treat moderate to severe pain. It is made from morphine and binds to opioid receptors in the central nervous system. Oxycodone hydrochloride is a type of analgesic agent and a type of opiate.

Display Name: Oxycodone Hydrochloride

Label: Oxycodone Hydrochloride

NCI Thesaurus Code: C48010 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0722364  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride
Oxecta
Oxycodone Hydrochloride
OXYCODONE HYDROCHLORIDE
oxycodone hydrochloride
OxyContin
Roxicodone

External Source Codes: 
CAS Registry Number 124-90-3 (see NLM ChemIDplus info)
FDA UNII Code C1ENJ2TE6C
ChEBI ID CHEBI:7859 (see ChEBI info)
PDQ Closed Trial Search ID 508980
PDQ Open Trial Search ID 508980 (check for NCI PDQ open clinical trial info)
UMLS CUI C0722364

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Pain
Chemical_Formula C18H21NO4.HCl
code C48010
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Oxycodone_Hydrochloride
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48010

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