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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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Fentanyl Citrate (Code C47994)

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Terms & Properties

Preferred Name: Fentanyl Citrate

Definition: The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression.

NCI-GLOSS Definition: A drug used to treat severe cancer pain in that occurs even though the patient is already taking opioids. It is also used during anesthesia for surgery. Fentanyl citrate binds to opioid receptors in the central nervous system. It is a type of analgesic agent and a type of opioid.

Display Name: Fentanyl Citrate

Label: Fentanyl Citrate

NCI Thesaurus Code: C47994 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0546864  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Fentanyl Citrate
fentanyl citrate

External Source Codes: 
CAS Registry Number 990-73-8 (see NLM ChemIDplus info)
ChEBI ID CHEBI:31602 (see ChEBI info)
PDQ Closed Trial Search ID 39241
PDQ Open Trial Search ID 39241 (check for NCI PDQ open clinical trial info)
UMLS CUI C0546864

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For breakthrough pain in cancer patients.
Chemical_Formula C22H28N2O.C6H8O7
code C47994
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Fentanyl_Citrate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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