|Clonidine Hydrochloride (Code C47979)|
|Terms & Properties|
Preferred Name: Clonidine Hydrochloride
Definition: The hydrochloride salt form of clonidine, an imidazoline derivate and centrally-acting alpha-adrenergic agonist as well as antagonist with antihypertensive activity. Clonidine hydrochloride binds to and stimulates central alpha-2 adrenergic receptors, thereby decreasing sympathetic outflow to the heart, kidneys, and peripheral vasculature. The reduction in sympathetic outflow, leads to decreased peripheral vascular resistance, decreased blood pressure, and decreased heart rate.
NCI-GLOSS Definition: A drug used to treat high blood pressure. It is also being studied in the treatment of certain types of cancer pain. It blocks the release of chemicals from nerve endings that make blood vessels constrict (get narrower). Catapres is a type of antihypertensive agent and a type of alpha-adrenergic agonist.
Label: Clonidine Hydrochloride
NCI Metathesaurus Link: C0546860 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||4205-91-8 (see NLM ChemIDplus info)|
|FDA UNII Code||W76I6XXF06|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|