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Version: 16.10e (Release date: 2016-10-31)
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Acyclovir Sodium (Code C47956)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Acyclovir Sodium

Definition: The sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.

Display Name: Acyclovir Sodium

Label: Acyclovir Sodium

NCI Thesaurus Code: C47956 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0592290  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one Momsodium Salt
9-((2-Hydroxyethoxy)methyl)guanine Monosodium Salt
Acyclovir Sodium
ACYCLOVIR SODIUM
Zovirax for Injection

External Source Codes: 
CAS Registry Number 69657-51-8 (see NLM ChemIDplus info)
FDA UNII Code 927L42J563
PDQ Closed Trial Search ID 531923
PDQ Open Trial Search ID 531923 (check for NCI PDQ open clinical trial info)
UMLS CUI C0592290

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C8H10N5O3.Na
code C47956
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Acyclovir_Sodium
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47956

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