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Version: 16.12d (Release date: 2016-12-27)
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Therapeutic Estradiol (Code C478)

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Terms & Properties

Preferred Name: Therapeutic Estradiol

Definition: A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability.

Display Name: Therapeutic Estradiol

Label: Therapeutic Estradiol

NCI Thesaurus Code: C478 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0699359  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
17 Beta-Estradiol
Aquadiol
Dimenformon
Diogyn
Diogynets
Estrace
ESTRADIOL
Estraldine
Oestradiol
Ovocylin
Progynon
Therapeutic Estradiol
Vagifem

External Source Codes: 
CAS Registry Number 50-28-2 (see NLM ChemIDplus info)
FDA UNII Code 4TI98Z838E
ChEBI ID CHEBI:16469 (see ChEBI info)
NSC Code 20293 (see NCI DTP info)
NSC Code 9895 (see NCI DTP info)
PDQ Closed Trial Search ID 39236
PDQ Open Trial Search ID 39236 (check for NCI PDQ open clinical trial info)
UMLS CUI C0699359

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C18H24O2
code C478
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Therapeutic_Estradiol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C478

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