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Version: 17.06d (Release date: 2017-06-26)
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Mepivacaine Hydrochloride (Code C47602)

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Terms & Properties

Preferred Name: Mepivacaine Hydrochloride

Definition: The hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties. At the injection site, mepivacaine hydrochloride acts by binding to specific membrane sodium ion channels in the neuronal cell membranes, thereby inhibiting sodium influx. This leads to a blockage of nerve impulse conduction and results in a loss of sensation.

Label: Mepivacaine Hydrochloride

NCI Thesaurus Code: C47602 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0700542  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(1-Methyl-DL-piperidine-2-carboxylic acid)-2,6-dimethylanilide hydrochloride
1-Methyl-2',6'-pipecoloxylidide Monohydrochloride
Carbocaine
Mepivacaine Hydrochloride
MEPIVACAINE HYDROCHLORIDE

External Source Codes: 
CAS Registry Number 1722-62-9 (see NLM ChemIDplus info)
FDA UNII Code 4VFX2L7EM5
ChEBI ID CHEBI:6760 (see ChEBI info)
PDQ Closed Trial Search ID 751573
PDQ Open Trial Search ID 751573 (check for NCI PDQ open clinical trial info)
UMLS CUI C0700542

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C15H22N2O.HCl
code C47602
Contributing_Source FDA
Legacy_Concept_Name Mepivacaine_Hydrochloride
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47602

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