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Version: 17.06d (Release date: 2017-06-26)
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Erythromycin (Code C476)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Erythromycin

Definition: A broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome. This prevents bacterial protein synthesis. Erythromycin may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved.

Label: Erythromycin

NCI Thesaurus Code: C476 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0014806  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
E-Mycin
Ery-Tab
Eryc
ERYC
EryDerm
Eryderm
ERYTHROMYCIN
Erythromycin
Ilotycin
Robimycin
RP-Mycin

External Source Codes: 
CAS Registry Number 114-07-8 (see NLM ChemIDplus info)
FDA UNII Code 63937KV33D
ChEBI ID CHEBI:42355 (see ChEBI info)
NSC Code 55929 (see NCI DTP info)
PDQ Closed Trial Search ID 39234
PDQ Open Trial Search ID 39234 (check for NCI PDQ open clinical trial info)
UMLS CUI C0014806

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C37H67NO13
code C476
Contributing_Source FDA
Legacy_Concept_Name Erythromycin
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C476

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