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Version: 17.12d (Release date: 2017-12-26)
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Ketoprofen (Code C47578)

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Terms & Properties

Preferred Name: Ketoprofen

Definition: A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Display Name: Ketoprofen

Label: Ketoprofen

NCI Thesaurus Code: C47578 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0022635  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Benzeneacetic Acid, 3-benzoyl-alpha-methyl-
Propionic Acid, 2-(3-benzoylphenyl)-

External Source Codes: 
CAS Registry Number 22071-15-4 (see NLM ChemIDplus info)
FDA UNII Code 90Y4QC304K
ChEBI ID CHEBI:6128 (see ChEBI info)
PDQ Closed Trial Search ID 743614
PDQ Open Trial Search ID 743614 (check for NCI PDQ open clinical trial info)
UMLS CUI C0022635

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H14O3
code C47578
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Ketoprofen
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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