skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Galantamine Hydrobromide (Code C47546)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Galantamine Hydrobromide

Definition: The hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.

Label: Galantamine Hydrobromide

NCI Thesaurus Code: C47546 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0949312  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Benzofuro(4,3,2-efg)(2)benzazocin-6-ol, 1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-, Hydrobromide
Galantamine Hydrobromide
Lycoremine Hydrobromide

External Source Codes: 
CAS Registry Number 1953-04-4 (see NLM ChemIDplus info)
CAS Registry Number 69353-21-5 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 739214
PDQ Open Trial Search ID 739214 (check for NCI PDQ open clinical trial info)
UMLS CUI C0949312

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C17H21NO3.BrH
code C47546
Contributing_Source FDA
Legacy_Concept_Name Galantamine_Hydrobromide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom