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Version: 16.11d (Release date: 2016-11-28)
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Fondaparinux Sodium (Code C47539)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Fondaparinux Sodium

Definition: The sodium salt form of fondaparinux, a synthetic glucopyranoside with antithrombotic activity. Fondaparinux sodium selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. (NCI05)

NCI-GLOSS Definition: A drug used to prevent blood clots from forming inside blood vessels in the leg. It is being studied in the prevention of blood clots in some cancer patients, including women having surgery for cancer of the reproductive tract. It is a type of anticoagulant.

Display Name: Fondaparinux Sodium

Label: Fondaparinux Sodium

NCI Thesaurus Code: C47539 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1099664  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Arixtra
fondaparinux
Fondaparinux Sodium
FONDAPARINUX SODIUM
fondaparinux sodium
Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-O-beta-D-glucopyra-nuronosyl-(1->4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1->4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, decasodium salt

External Source Codes: 
CAS Registry Number 114870-03-0 (see NLM ChemIDplus info)
FDA UNII Code X0Q6N9USOZ
ChEBI ID CHEBI:31632 (see ChEBI info)
PDQ Closed Trial Search ID 510285
PDQ Open Trial Search ID 510285 (check for NCI PDQ open clinical trial info)
UMLS CUI C1099664

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C31H43N3O49S8.10Na
code C47539
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Fondaparinux_Sodium
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47539

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