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Version: 17.06d (Release date: 2017-06-26)
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Escitalopram Oxalate (Code C47518)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Escitalopram Oxalate

Definition: The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity.

NCI-GLOSS Definition: A drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called selective serotonin reuptake inhibitors (SSRIs).

Display Name: Escitalopram Oxalate

Label: Escitalopram Oxalate

NCI Thesaurus Code: C47518 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1170746  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1)
escitalopram
Escitalopram Oxalate
ESCITALOPRAM OXALATE
Lexapro
Lu 26-054-0

External Source Codes: 
CAS Registry Number 219861-08-2 (see NLM ChemIDplus info)
FDA UNII Code 5U85DBW7LO
PDQ Closed Trial Search ID 497135
PDQ Open Trial Search ID 497135 (check for NCI PDQ open clinical trial info)
UMLS CUI C1170746

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Major Depressive Disorder in Adolescents
Chemical_Formula C20H21FN2O.C2H2O4
code C47518
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Escitalopram_Oxalate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47518

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