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Version: 16.11d (Release date: 2016-11-28)
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Dexpanthenol (Code C47481)

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Terms & Properties

Preferred Name: Dexpanthenol

Definition: An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

Label: Dexpanthenol

NCI Thesaurus Code: C47481 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0057610  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
d-Pantothenol
D-Pantothenyl Alcohol
DEXPANTHENOL
Dexpanthenol
Ilopan
Motilyn
Pantenyl
Provitamin B5

External Source Codes: 
CAS Registry Number 81-13-0 (see NLM ChemIDplus info)
FDA UNII Code 1O6C93RI7Z
ChEBI ID CHEBI:27373 (see ChEBI info)
NSC Code 302962 (see NCI DTP info)
UMLS CUI C0057610

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C9H19NO4
code C47481
Contributing_Source FDA
Legacy_Concept_Name Dexpanthenol
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47481

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