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Version: 17.06d (Release date: 2017-06-26)
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Desflurane (Code C47472)

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Terms & Properties

Preferred Name: Desflurane

Definition: A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matrix of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

Label: Desflurane

NCI Thesaurus Code: C47472 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0063252  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Desflurane
DESFLURANE
Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-
I 653
Suprane

External Source Codes: 
CAS Registry Number 57041-67-5 (see NLM ChemIDplus info)
FDA UNII Code CRS35BZ94Q
ChEBI ID CHEBI:4445 (see ChEBI info)
PDQ Closed Trial Search ID 574264
PDQ Open Trial Search ID 574264 (check for NCI PDQ open clinical trial info)
UMLS CUI C0063252

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C3H2F6O
code C47472
Contributing_Source FDA
Legacy_Concept_Name Desflurane
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47472

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