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Version: 17.06d (Release date: 2017-06-26)
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Atomoxetine Hydrochloride (Code C47405)

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Terms & Properties

Preferred Name: Atomoxetine Hydrochloride

Definition: The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.

Label: Atomoxetine Hydrochloride

NCI Thesaurus Code: C47405 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1170741  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(-)-N-methyl-gamma(2-methylphenoxy)benzenepropamine Hydrochloride
(-)-N -Methyl-3-phenyl-3-(o-tolyloxy)-propylamine Hydrochloride
ATOMOXETINE HYDROCHLORIDE
Atomoxetine Hydrochloride
Strattera
Tomoxetine

External Source Codes: 
CAS Registry Number 82248-59-7 (see NLM ChemIDplus info)
FDA UNII Code 57WVB6I2W0
ChEBI ID CHEBI:331697 (see ChEBI info)
PDQ Closed Trial Search ID 475797
PDQ Open Trial Search ID 475797 (check for NCI PDQ open clinical trial info)
UMLS CUI C1170741

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C17H21NO.ClH
code C47405
Contributing_Source FDA
Legacy_Concept_Name Atomoxetine_Hydrochloride
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C47405

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