skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Dipyridamole (Code C445)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Dipyridamole

Definition: A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04)

NCI-GLOSS Definition: A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents.

Label: Dipyridamole

NCI Thesaurus Code: C445 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0012582  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol
Dipyridamole
DIPYRIDAMOLE
dipyridamole
DP
Persantine

External Source Codes: 
CAS Registry Number 58-32-2 (see NLM ChemIDplus info)
FDA UNII Code 64ALC7F90C
ChEBI ID CHEBI:4653 (see ChEBI info)
NSC Code 515776 (see NCI DTP info)
PDQ Closed Trial Search ID 39229
PDQ Open Trial Search ID 39229 (check for NCI PDQ open clinical trial info)
UMLS CUI C0012582

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C24H40N8O4
code C445
Contributing_Source FDA
Legacy_Concept_Name Dipyridamole
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C445

Mainbox Bottom