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Version: 17.06d (Release date: 2017-06-26)
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Dextromethorphan Hydrobromide (Code C423)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Dextromethorphan Hydrobromide

Definition: The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.

Display Name: Dextromethorphan Hydrobromide

Label: Dextromethorphan Hydrobromide

NCI Thesaurus Code: C423 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0350422  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Dextromethorphan Hydrobromide
DEXTROMETHORPHAN HYDROBROMIDE

External Source Codes: 
CAS Registry Number 6700-34-1 (see NLM ChemIDplus info)
FDA UNII Code 9D2RTI9KYH
NSC Code 34521 (see NCI DTP info)
PDQ Closed Trial Search ID 42490
PDQ Open Trial Search ID 42490 (check for NCI PDQ open clinical trial info)
UMLS CUI C0350422

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C18H25NO.BrH.H2O
code C423
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Dextromethorphan
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C423

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