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Version: 17.06d (Release date: 2017-06-26)
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Deferoxamine Mesylate (Code C417)

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Terms & Properties

Preferred Name: Deferoxamine Mesylate

Definition: The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome.

Display Name: Deferoxamine Mesylate

Label: Deferoxamine Mesylate

NCI Thesaurus Code: C417 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0011148  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Deferoxamine B
Deferoxamine Mesylate
Deferoxamine mesylate
DEFEROXAMINE MESYLATE
Deferoxamine Methanesulfonate
Deferrioxamine B
Desferal
Desferrioxamine Mesylate
DFM

External Source Codes: 
CAS Registry Number 138-14-7 (see NLM ChemIDplus info)
FDA UNII Code V9TKO7EO6K
ChEBI ID CHEBI:31460 (see ChEBI info)
NSC Code 644468 (see NCI DTP info)
PDQ Closed Trial Search ID 41696
PDQ Open Trial Search ID 41696 (check for NCI PDQ open clinical trial info)
UMLS CUI C0011148

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C25H48N6O8.CH4O3S
code C417
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Deferoxamine_Mesylate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C417

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