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National Cancer Institute
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Version: 16.11d (Release date: 2016-11-28)
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CC-8490 (Code C38711)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: CC-8490

Definition: A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04)

NCI-GLOSS Definition: A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called benzopyrans.

Label: CC-8490

NCI Thesaurus Code: C38711 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1328106  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
CC-8490
SPC8490

External Source Codes: 
PDQ Closed Trial Search ID 346082
PDQ Open Trial Search ID 346082 (check for NCI PDQ open clinical trial info)
UMLS CUI C1328106

Other Properties:
Name Value (qualifiers indented underneath)
code C38711
Legacy_Concept_Name CC-8490
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38711

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