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Version: 17.06d (Release date: 2017-06-26)
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Fowlpox-PSA-TRICOM Vaccine (Code C38708)

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Terms & Properties

Preferred Name: Fowlpox-PSA-TRICOM Vaccine

Definition: A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA) and TRICOM, a combination of three immunostimulants (i.e., B7.1, ICAM-1, and LFA-3). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.

Label: Fowlpox-PSA-TRICOM Vaccine

NCI Thesaurus Code: C38708 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327972  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Fowlpox-PSA-TRICOM Vaccine
fPSA-TRI

External Source Codes: 
UMLS CUI C1327972

Other Properties:
     Name Value (qualifiers indented underneath)
code C38708
Legacy_Concept_Name Fowlpox-PSA-TRICOM_Vaccine
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38708

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