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Version: 17.06d (Release date: 2017-06-26)
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Lutetium Lu 177 Monoclonal Antibody J591 (Code C38701)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Lutetium Lu 177 Monoclonal Antibody J591

Definition: A radioimmunoconjugate consisting of a humanized monoclonal antibody directed against the extracellular domain of prostate-specific membrane antigen linked to a beta-emitting radioisotope (lutetium-177). This radioimmunoconjugate binds to tumor cells that express the extracellular domain of prostate-specific membrane antigen, delivering beta particle radiation selectively to tumor cells expressing this antigen and so limiting the exposure of normal tissues to ionizing radiation.

Display Name: Lutetium Lu 177 Monoclonal Antibody J591

Label: Lutetium Lu 177 Monoclonal Antibody J591

NCI Thesaurus Code: C38701 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1518042  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Lutetium Lu 177 Monoclonal Antibody J591
Lu 177 MOAB J591

External Source Codes: 
PDQ Closed Trial Search ID 361550
PDQ Open Trial Search ID 361550 (check for NCI PDQ open clinical trial info)
UMLS CUI C1518042

Other Properties:
     Name Value (qualifiers indented underneath)
code C38701
Contributing_Source CTRP
Legacy_Concept_Name Lutetium_Lu_177_Monoclonal_Antibody_J591
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38701

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