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Version: 16.11d (Release date: 2016-11-28)
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Moxifloxacin Hydrochloride (Code C38696)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Moxifloxacin Hydrochloride

Definition: The hydrochloride salt of a fluoroquinolone antibacterial antibiotic. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species.

NCI-GLOSS Definition: A drug used to treat bacterial infections. It is a type of fluoroquinolone.

Display Name: Moxifloxacin Hydrochloride

Label: Moxifloxacin Hydrochloride

NCI Thesaurus Code: C38696 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0754517  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Avelox
BAY 128039
Moxeza
Moxifloxacin Hydrochloride
MOXIFLOXACIN HYDROCHLORIDE
Vigamox

External Source Codes: 
CAS Registry Number 186826-86-8 (see NLM ChemIDplus info)
FDA UNII Code C53598599T
ChEBI ID CHEBI:7008 (see ChEBI info)
PDQ Closed Trial Search ID 306456
PDQ Open Trial Search ID 306456 (check for NCI PDQ open clinical trial info)
UMLS CUI C0754517

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Various bacterial infections; Bacterial Conjunctivitis
Chemical_Formula C21H24FN3O4.HCl
code C38696
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Moxifloxacin
Semantic_Type Antibiotic

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38696

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