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Version: 17.06d (Release date: 2017-06-26)
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Ravuconazole (Code C38688)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ravuconazole

Definition: A triazole with antifungal activity. Ravuconazole inhibits 14a demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCI04)

NCI-GLOSS Definition: A substance that is being studied in the treatment of infections caused by fungi. It belongs to the family of drugs called antifungal agents.

Label: Ravuconazole

NCI Thesaurus Code: C38688 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0535186  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BMS-207147
ER-30346
p-(2-((alphaR,betaR)-2,4-Difluoro-beta-hydroxy-alpha-methyl-beta-(1H-1,2,4-triazol-1-ylmethyl)phenethyl)-4-thiazolyl)benzonitrile
Ravuconazole
ravuconazole
RAVUCONAZOLE

External Source Codes: 
CAS Registry Number 182760-06-1 (see NLM ChemIDplus info)
FDA UNII Code 95YH599JWV
PDQ Closed Trial Search ID 315643
PDQ Open Trial Search ID 315643 (check for NCI PDQ open clinical trial info)
UMLS CUI C0535186

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C22H17F2N5OS
code C38688
Contributing_Source FDA
Legacy_Concept_Name Ravuconazole
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38688

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