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Version: 17.06d (Release date: 2017-06-26)
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Ferumoxtran-10 (Code C38140)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ferumoxtran-10

Definition: A synthetic ultrasmall superparamagnetic iron oxide composed of dextran-coated iron oxide nanoparticles (also known as 'ultrasmall particulate iron oxides' or USPIO). Ferumoxtran-10, which accumulates in non-cancerous lymphatic tissue, is used as a molecular resonance imaging (MRI) contrast agent. (NCI04)

NCI-GLOSS Definition: A substance being studied as a way of improving magnetic resonance imaging (MRI) in diagnosing cancer and finding lymph nodes to which cancer has spread. Ferumoxtran-10 is made of nanoparticles (ultrasmall pieces) of iron oxide coated with dextran (a type of sugar). It is injected into the blood of the patient and the particles collect in lymph nodes, liver, spleen, or brain tissue where they can be seen using MRI. Ferumoxtran-10 later breaks down and passes from the body in urine.

Display Name: Ferumoxtran-10

Label: Ferumoxtran-10

NCI Thesaurus Code: C38140 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0386370  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Combidex
Ferumoxtran-10
ferumoxtran-10
Ultrasmall Particulate Iron Oxide
USPIO

External Source Codes: 
NSC Code 731411 (see NCI DTP info)
PDQ Closed Trial Search ID 423355
PDQ Open Trial Search ID 423355 (check for NCI PDQ open clinical trial info)
UMLS CUI C0386370

Other Properties:
     Name Value (qualifiers indented underneath)
code C38140
Contributing_Source CTRP
Legacy_Concept_Name Ferumoxtran-10
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38140

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