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Version: 17.06d (Release date: 2017-06-26)
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NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG (Code C37507)

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Terms & Properties

Preferred Name: NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG

Definition: A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis antigen (NY-ESO-1) and emulsified in the immunoadjuvant Montanide ISA-51 VG, with potential immunomodulating and antineoplastic activities. Upon subcutaneous vaccination, the NY-ESO-1 protein vaccine emulsified in Montanide ISA-51 VG may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1, an antigen found in normal testes and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. The surfactant mannide monooleate in Montanide ISA 51 VG is derived from vegetable-grade (VG) oleic acid that was purified from olive oil.

Display Name: NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG

Label: NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG

NCI Thesaurus Code: C37507 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL437036  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
NY-ESO-1 Protein Vaccine Emulsified In Montanide ISA-51 VG
NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG

External Source Codes: 
PDQ Closed Trial Search ID 736208
PDQ Open Trial Search ID 736208 (check for NCI PDQ open clinical trial info)
NCI META CUI CL437036

Other Properties:
     Name Value (qualifiers indented underneath)
code C37507
Contributing_Source CTRP
Legacy_Concept_Name Montanide-ISA-51_NY-ESO-1-Peptide-Vaccine
Semantic_Type Therapeutic or Preventive Procedure

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C37507

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