skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 16.11d (Release date: 2016-11-28)
SearchBox Top
SearchBox Bottom
Efaproxiral (Code C37453)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Concept Status: Retired Concept  (See:  Efaproxiral )

Preferred Name: Efaproxiral

Definition: A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04)

Label: Efaproxiral

NCI Thesaurus Code: C37453 (Search for linked caDSR metadata)  (search value sets)

Synonyms & Abbreviations: (see Synonym Details)
Efaproxiral
RSR13

External Source CodesNone

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Radiosensitizer, adjuvant to whole brain radiation therapy
code C37453
Concept_Status Retired_Concept
DesignNote Merged with RSR-13
OLD_KIND Chemicals_and_Drugs_Kind
OLD_PARENT Radiosensitizing_Agent
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C37453

Mainbox Bottom