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Version: 16.10e (Release date: 2016-10-31)
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NA17-A Antigen (Code C37450)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: NA17-A Antigen

Definition: A specific melanoma antigen protein derived from a patient (NA17) with cutaneous melanoma metastases. When administered in a vaccine formulation, NA17-A antigen may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size. The NA17-A antigen is part of the enzyme N-acetyl glucosaminyltransferase V (GnT-V). Approximately half of melanomas have been found to express significant levels of this atypical protein, which is not expressed by normal tissues.

Label: NA17-A Antigen

NCI Thesaurus Code: C37450 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1134655  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
NA17-A
NA17-A Antigen

External Source Codes: 
PDQ Closed Trial Search ID 38647
PDQ Open Trial Search ID 38647 (check for NCI PDQ open clinical trial info)
UMLS CUI C1134655

Other Properties:
Name Value (qualifiers indented underneath)
code C37450
Legacy_Concept_Name NA17-A_Antigen
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C37450

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