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Version: 17.06d (Release date: 2017-06-26)
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Carbamazepine (Code C341)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Carbamazepine

Definition: A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.

Label: Carbamazepine

NCI Thesaurus Code: C341 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0006949  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
5H-Dibenz(b,f)azepine-5-carboxamide
Carbamazepine
CARBAMAZEPINE
Epitol
Tegretol

External Source Codes: 
CAS Registry Number 298-46-4 (see NLM ChemIDplus info)
FDA UNII Code 33CM23913M
ChEBI ID CHEBI:3387 (see ChEBI info)
NSC Code 169864 (see NCI DTP info)
PDQ Closed Trial Search ID 42418
PDQ Open Trial Search ID 42418 (check for NCI PDQ open clinical trial info)
UMLS CUI C0006949

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Epilepsy
Chemical_Formula C15H12N2O
code C341
Contributing_Source FDA
Legacy_Concept_Name Carbamazepine
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C341

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