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Version: 17.06d (Release date: 2017-06-26)
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Calcium Saccharate (Code C335)

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Terms & Properties

Preferred Name: Calcium Saccharate

Definition: The calcium salt form of glucaric acid, a natural substance found in many fruits and vegetables, with potential anti-cancer property. One of the key processes in which the human body eliminates toxic chemicals as well as hormones (such as estrogen) is by attaching glucuronic acid to them in the liver and then excreting the complex in the bile. When beta-glucuronidase breaks the bond, it prolongs the stay of the hormone or toxic chemical in the body. Elevated beta-glucuronidase activity has been implicated to be associated with an increased risk for hormone-dependent cancers like breast, prostate, and colon cancers. Therefore, supplementing calcium glucarate may suppress the developments of hormone-dependent cancers.

Display Name: Calcium Saccharate

Label: Calcium Saccharate

NCI Thesaurus Code: C335 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0771997  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2,3,4,5-tetrahydroxy-1,6- dioxido-hexane-1,6-dione, Calcium
Antacidin
Calcium D-Glucarate
Calcium D-Saccharate
Calcium Glucarate
Calcium Saccharate
CALCIUM SACCHARATE
CGT
D-Glucaric Acid, Calcium Salt (1:1)
Saccharated Lime

External Source Codes: 
CAS Registry Number 5793-89-5 (see NLM ChemIDplus info)
FDA UNII Code 6AP9J91K4V
NSC Code 122011 (see NCI DTP info)
PDQ Closed Trial Search ID 41803
PDQ Open Trial Search ID 41803 (check for NCI PDQ open clinical trial info)
UMLS CUI C0771997

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C6H8O8.Ca.4H2O
code C335
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Calcium_Glucarate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C335

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