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Version: 17.06d (Release date: 2017-06-26)
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Betamethasone (Code C303)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Betamethasone

Definition: A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

Label: Betamethasone

NCI Thesaurus Code: C303 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0005308  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BETAMETHASONE
Betamethasone
Celestone

External Source Codes: 
CAS Registry Number 378-44-9 (see NLM ChemIDplus info)
FDA UNII Code 9842X06Q6M
ChEBI ID CHEBI:3077 (see ChEBI info)
NSC Code 39470 (see NCI DTP info)
PDQ Closed Trial Search ID 39273
PDQ Open Trial Search ID 39273 (check for NCI PDQ open clinical trial info)
UMLS CUI C0005308

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C22H29FO5
code C303
Contributing_Source FDA
Legacy_Concept_Name Betamethasone
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C303

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