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Version: 17.12d (Release date: 2017-12-26)
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Beclomethasone Dipropionate (Code C299)

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Terms & Properties

Preferred Name: Beclomethasone Dipropionate

Definition: The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

Display Name: Beclomethasone Dipropionate

Label: Beclomethasone Dipropionate

NCI Thesaurus Code: C299 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0004906  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione Dipropionate
Beclomethasone Dipropionate

External Source Codes: 
CAS Registry Number 5534-09-8 (see NLM ChemIDplus info)
FDA UNII Code 5B307S63B2
ChEBI ID CHEBI:3002 (see ChEBI info)
PDQ Closed Trial Search ID 39272
PDQ Open Trial Search ID 39272 (check for NCI PDQ open clinical trial info)
UMLS CUI C0004906

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Asthma; GI graft vs. host disease, prevention; Nasal polyps; Rhinitis
Chemical_Formula C28H37ClO7
code C299
Contributing_Source CTRP
Contributing_Source FDA
Contributing_Source HL7
Legacy_Concept_Name Beclomethasone
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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