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Version: 17.06d (Release date: 2017-06-26)
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BCG Vaccine (Code C298)

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Terms & Properties

Preferred Name: BCG Vaccine

Definition: A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis.

NICHD Definition: A tuberculosis vaccine containing bacillus Calmette-Guérin, a live attenuated strain of Mycobacterium bovis. There are many different strains of BCG vaccine, all of which were originally derived from one strain, but which now have very different properties.

NCI-GLOSS Definition: A weakened form of the bacterium Mycobacterium bovis (bacillus Calmette-Guerin) that does not cause disease. BCG is used in a solution to stimulate the immune system in the treatment of bladder cancer and as a vaccine to prevent tuberculosis.

Display Name: BCG Vaccine

Label: BCG Vaccine

NCI Thesaurus Code: C298 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0004886  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Bacille Calmette-Guerin Live
Bacillius Calmette-Guerin Vaccine
Bacillus Calmette-Guerin
Bacillus Calmette-Guérin Vaccine
Bacillus Calmette Guerin
BCG (Pasteur)
BCG Tice
BCG Vaccine
Cultivo BCG
Imovax BCG
Live Intravesical BCG
Mycobacterium bovis (Strain BCG)

External Source Codes: 
NSC Code 116341 (see NCI DTP info)
NSC Code 614389 (see NCI DTP info)
NSC Code 116328 (see NCI DTP info)
PDQ Closed Trial Search ID 43028
PDQ Open Trial Search ID 43028 (check for NCI PDQ open clinical trial info)
UMLS CUI C0004886

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Bladder cancer; Tuberculosis, immunization
Accepted_Therapeutic_Use_For Immunoadjuvant in Vaccine Therapy
code C298
Contributing_Source CTRP
Contributing_Source NICHD
Legacy_Concept_Name BCG_Vaccine
NICHD_Hierarchy_Term Bacillus Calmette-Guérin Vaccine
Semantic_Type Bacterium
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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