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Version: 16.10e (Release date: 2016-10-31)
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Tamsulosin Hydrochloride (Code C29486)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Tamsulosin Hydrochloride

Definition: The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate.

NCI-GLOSS Definition: A drug used to treat urinary problems caused by an enlarged prostate. Flomax relaxes the muscles of the prostate and bladder, which helps the flow of urine. It is a type of alpha blocker.

Label: Tamsulosin Hydrochloride

NCI Thesaurus Code: C29486 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0771774  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Flomax
TAMSULOSIN HYDROCHLORIDE
Tamsulosin Hydrochloride
tamsulosin hydrochloride

External Source Codes: 
CAS Registry Number 106463-17-6 (see NLM ChemIDplus info)
FDA UNII Code 11SV1951MR
ChEBI ID CHEBI:9399 (see ChEBI info)
PDQ Closed Trial Search ID 479148
PDQ Open Trial Search ID 479148 (check for NCI PDQ open clinical trial info)
UMLS CUI C0771774

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Benign Prostatic Hyperplasia
Chemical_Formula C20H28N2O5S.HCl
code C29486
Contributing_Source FDA
Legacy_Concept_Name Tamsulosin_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29486

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