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Version: 17.06d (Release date: 2017-06-26)
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Sertraline Hydrochloride (Code C29451)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Sertraline Hydrochloride

Definition: The hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS.

NCI-GLOSS Definition: A drug used to treat depression. It is a type of selective serotonin reuptake inhibitor (SSRI).

Display Name: Sertraline Hydrochloride

Label: Sertraline Hydrochloride

NCI Thesaurus Code: C29451 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0600526  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Sertraline Hydrochloride
SERTRALINE HYDROCHLORIDE
Zoloft

External Source Codes: 
CAS Registry Number 79559-97-0 (see NLM ChemIDplus info)
FDA UNII Code UTI8907Y6X
ChEBI ID CHEBI:9124 (see ChEBI info)
PDQ Closed Trial Search ID 322832
PDQ Open Trial Search ID 322832 (check for NCI PDQ open clinical trial info)
UMLS CUI C0600526

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Major depressive disorder; Obsessive-compulsive disorder; Panic disorder; Posttraumatic stress disorder; Premenstrual dysphoric disorder; Social phobia
Chemical_Formula C17H17Cl2N.HCl
code C29451
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Sertraline_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29451

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