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Version: 16.11d (Release date: 2016-11-28)
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Propofol (Code C29384)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Propofol

Definition: A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.

Display Name: Propofol

Label: Propofol

NCI Thesaurus Code: C29384 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0033487  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Diprivan
Propofol
PROPOFOL

External Source Codes: 
CAS Registry Number 2078-54-8 (see NLM ChemIDplus info)
FDA UNII Code YI7VU623SF
ChEBI ID CHEBI:44915 (see ChEBI info)
NSC Code 5105 (see NCI DTP info)
PDQ Closed Trial Search ID 461189
PDQ Open Trial Search ID 461189 (check for NCI PDQ open clinical trial info)
UMLS CUI C0033487

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C12H18O
code C29384
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Propofol
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29384

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