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Version: 17.06d (Release date: 2017-06-26)
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Mesalamine (Code C29249)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Mesalamine

Definition: An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04)

Display Name: Mesalamine

Label: Mesalamine

NCI Thesaurus Code: C29249 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0127615  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
5-Amino-2-hydroxybenzoic Acid
5-Aminosalicylic Acid
5-ASA
Apriso
Asacol
Lialda
Mesalamine
MESALAMINE
Mesalazine
Pentasa
Rowasa

External Source Codes: 
CAS Registry Number 89-57-6 (see NLM ChemIDplus info)
FDA UNII Code 4Q81I59GXC
ChEBI ID CHEBI:6775 (see ChEBI info)
NSC Code 38877 (see NCI DTP info)
PDQ Closed Trial Search ID 732182
PDQ Open Trial Search ID 732182 (check for NCI PDQ open clinical trial info)
UMLS CUI C0127615

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Ulcerative Colitis and Proctitis
Chemical_Formula C7H7NO3
code C29249
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Mesalamine
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29249

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