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Version: 17.08d (Release date: 2017-08-28)
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Magnesium Oxide (Code C29242)

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Terms & Properties

Preferred Name: Magnesium Oxide

Definition: The oxide salt of magnesium with antacid, laxative and vascular smooth muscle relaxant activities. Magnesium combines with water to form magnesium hydroxide which reacts chemically to neutralize or buffer existing quantities of stomach acid; stomach-content and intra-esophageal pH rise, resulting in a decrease in pepsin activity. This agent's laxative effect is the result, in part, of osmotically mediated water retention, which subsequently stimulates peristalsis. In addition, magnesium ions may behave as calcium antagonists in vascular smooth muscle.

Display Name: Magnesium Oxide

Label: Magnesium Oxide

NCI Thesaurus Code: C29242 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0024477  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Magnesium Oxide

External Source Codes: 
CAS Registry Number 1309-48-4 (see NLM ChemIDplus info)
ChEBI ID CHEBI:31794 (see ChEBI info)
PDQ Closed Trial Search ID 658594
PDQ Open Trial Search ID 658594 (check for NCI PDQ open clinical trial info)
UMLS CUI C0024477

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula Mg.O
code C29242
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Magnesium_Oxide
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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