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Version: 17.12d (Release date: 2017-12-26)
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Magnesium Citrate (Code C29241)

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Terms & Properties

Preferred Name: Magnesium Citrate

Definition: The citrate salt of the element magnesium with cathartic activity. The cathartic action of magnesium cations appears to result, in part, from osmotically mediated water retention, which subsequently stimulates peristalsis. In addition, magnesium ions may also stimulate the activity of nitric oxide (NO) synthase and increase the biosynthesis of the phospholipid proinflammatory mediator platelet activating factor (PAF) in the gut. NO may stimulate intestinal secretion via prostaglandin- and cyclic GMP-dependent mechanisms while PAF produces significant stimulation of colonic secretion and gastrointestinal motility.

Label: Magnesium Citrate

NCI Thesaurus Code: C29241 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0126774  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Citrate of Magnesia
Magnesium Citrate

External Source Codes: 
CAS Registry Number 3344-18-1 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 480467
PDQ Open Trial Search ID 480467 (check for NCI PDQ open clinical trial info)
UMLS CUI C0126774

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula 2C6H5O7.3Mg
code C29241
Contributing_Source FDA
Legacy_Concept_Name Magnesium_Citrate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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