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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Linezolid (Code C29158)

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Terms & Properties

Preferred Name: Linezolid

Definition: A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. (NCI04)

Display Name: Linezolid

Label: Linezolid

NCI Thesaurus Code: C29158 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0663241  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
CAS Registry Number 165800-03-3 (see NLM ChemIDplus info)
ChEBI ID CHEBI:63607 (see ChEBI info)
PDQ Closed Trial Search ID 735710
PDQ Open Trial Search ID 735710 (check for NCI PDQ open clinical trial info)
UMLS CUI C0663241

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H20FN3O4
code C29158
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Linezolid
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  


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