skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Linezolid (Code C29158)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Linezolid

Definition: A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. (NCI04)

Display Name: Linezolid

Label: Linezolid

NCI Thesaurus Code: C29158 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0663241  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Linezolid
LINEZOLID
Zyvox

External Source Codes: 
CAS Registry Number 165800-03-3 (see NLM ChemIDplus info)
FDA UNII Code ISQ9I6J12J
ChEBI ID CHEBI:63607 (see ChEBI info)
PDQ Closed Trial Search ID 735710
PDQ Open Trial Search ID 735710 (check for NCI PDQ open clinical trial info)
UMLS CUI C0663241

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H20FN3O4
code C29158
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Linezolid
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29158

Mainbox Bottom