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Version: 17.12d (Release date: 2017-12-26)
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Laetrile (Code C29149)

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Terms & Properties

Preferred Name: Laetrile

Definition: Originally, the name laetrile was the contraction of laevo-mandelonitrile glucoside, a cyanogenic glycoside found naturally in some plants. Over the years the meaning of laetrile has changed. There are now preparations called Laetrile where amygdalin is the major constituent. Laetrile and amygdalin are often used interchangeably, but are different agents. Cyanide and benzaldehyde are metabolites of both laetrile and amygdalin. Both metabolites may possess antineoplastic properties. Laetrile has been used as an anticancer treatment in humans worldwide, but scientific evidence does not support its effectiveness. It is not approved for use in the United States. (NCI04)

NCI-GLOSS Definition: A substance found in the pits of many fruits such as apricots and papayas, and in other foods. It has been tried in some countries as a treatment for cancer, but it has not been shown to work in clinical studies. Laetrile is not approved for use in the United States.

Label: Laetrile

NCI Thesaurus Code: C29149 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0878244  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Beta-D-Glucopyranosiduronic acid, alpha-cyanobenzyl
Cyanophenylmethyl-beta-D-glucopyranosiduronic acid
Vitamin B17

External Source Codes: 
NSC Code 103055 (see NCI DTP info)
PDQ Closed Trial Search ID 257611
PDQ Open Trial Search ID 257611 (check for NCI PDQ open clinical trial info)
UMLS CUI C0878244

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C14-H15-N-O7
code C29149
Legacy_Concept_Name Laetrille
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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