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Version: 17.12d (Release date: 2017-12-26)
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Insulin Lispro (Code C29123)

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Terms & Properties

Preferred Name: Insulin Lispro

Definition: A recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration. Lispro insulin is equipotent to human insulin on a molar basis but its effects are faster and of shorter duration. Endogenous insulin, a pancreatic hormone composed of two polypeptide chains, is important in the normal metabolism of carbohydrates, proteins and fats, promoting glucose utilization and protein synthesis; it has anabolic effects on many types of tissues. (NCI04)

Label: Insulin Lispro

NCI Thesaurus Code: C29123 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0293359  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Insulin Lispro

External Source Codes: 
CAS Registry Number 133107-64-9 (see NLM ChemIDplus info)
UMLS CUI C0293359

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C257H383N65O77S6
code C29123
Contributing_Source FDA
Legacy_Concept_Name Lispo_Insulin
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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