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Version: 17.06d (Release date: 2017-06-26)
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6-Azauridine (Code C291)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: 6-Azauridine

Definition: A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis.

Label: 6-Azauridine

NCI Thesaurus Code: C291 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0004483  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl
2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H, 4H)-dione
3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine riboside
6-Azauracil-.beta.-D-riboside
6-azauracil-beta-D-riboside
6-azauracilriboside
6-Azauracilriboside
6-azauracil 1-riboside
6-Azauracil 1-riboside
6-azauracil riboside
6-Azauracil riboside
6-Azauridine
6-AZAURIDINE
Azauridine
Riboazauracil

External Source Codes: 
CAS Registry Number 54-25-1 (see NLM ChemIDplus info)
FDA UNII Code 7BVB29RCPR
ChEBI ID CHEBI:35668 (see ChEBI info)
NSC Code 32074 (see NCI DTP info)
PDQ Closed Trial Search ID 39158
PDQ Open Trial Search ID 39158 (check for NCI PDQ open clinical trial info)
UMLS CUI C0004483

Other Properties:
     Name Value (qualifiers indented underneath)
code C291
Contributing_Source FDA
Legacy_Concept_Name _6-Azauridine
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C291

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