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Version: 17.06d (Release date: 2017-06-26)
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Fluvoxamine Maleate (Code C29063)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Fluvoxamine Maleate

Definition: The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic neuronal membrane leading to an increase of serotonin levels within the synaptic cleft. This results in facilitated serotonergic transmission and decreased serotonin turnover leading to antidepressant and antiobsessive-compulsive effects.

NCI-GLOSS Definition: A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective serotonin reuptake inhibitor (SSRI).

Display Name: Fluvoxamine Maleate

Label: Fluvoxamine Maleate

NCI Thesaurus Code: C29063 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0700473  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Fluoxamine
Fluvoxamine Maleate
FLUVOXAMINE MALEATE
Luvox

External Source Codes: 
CAS Registry Number 61718-82-9 (see NLM ChemIDplus info)
FDA UNII Code 5LGN83G74V
PDQ Closed Trial Search ID 735770
PDQ Open Trial Search ID 735770 (check for NCI PDQ open clinical trial info)
UMLS CUI C0700473

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C15H21F3N2O2.C4H4O4
code C29063
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Fluvoxamine_Maleate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29063

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