skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Famotidine (Code C29045)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Famotidine

Definition: A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.

Display Name: Famotidine

Label: Famotidine

NCI Thesaurus Code: C29045 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0015620  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Famotidine
FAMOTIDINE
Pepcid
Pepcid AC

External Source Codes: 
CAS Registry Number 76824-35-6 (see NLM ChemIDplus info)
FDA UNII Code 5QZO15J2Z8
ChEBI ID CHEBI:4975 (see ChEBI info)
PDQ Closed Trial Search ID 574268
PDQ Open Trial Search ID 574268 (check for NCI PDQ open clinical trial info)
UMLS CUI C0015620

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C8H15N7O2S3
code C29045
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Famotidine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29045

Mainbox Bottom